Dr. Corey Nislow is a geneticist and cell biologist who has pioneered massively parallel screens of yeast to understand how genotype combines with the environment to influence phenotype. He and his team have constructed the largest chemogenomic yeast drug action network. Most recently, the Nislow lab has tested systematic yeast mutant collections in microgravity on the International Space Station and in the face of cosmic radiation on an upcoming round-trip mission to the moon. Data from these missions will be used to develop super-yeast capable of withstanding the stresses of long-term space survival.
Dr. Paula Gonçalves currently studies the evolution of metabolism using as a model the Wickerhamiella/Starmerella fructophilic yeast clade. Her lab focuses mainly on the role played by xenolog genes horizontally acquired from bacteria or from other fungi in the adaptation of metabolism in this clade.
Genome BC Keynote Lecturer
Dr. Jay Keasling is a pioneer in engineering microbes and metabolism. During the early 2000s, Dr. Keasling led a UC Berkeley research team to use engineered yeast to synthetically produce artemisinin, the powerful anti-malarial drug. Researchers at the Keasling Lab are now using the same technology to produce other pharmaceuticals, commodity chemicals, and cellulosic biofuels.
EMBO Keynote Lecturer
Prof. Ken Wolfe is an evolutionary geneticist interested in how yeast chromosomes and genomes are organised. He discovered the whole-genome duplication that occurred in an ancestor of Saccharomyces cerevisiae 100 million years ago. Recent work in his lab has focused on evolution of mating-type loci and on the origins of non-standard genetic codes in yeasts.